Correction for Grahammer et al., mTORC1 maintains renal tubular homeostasis and is essential in response to ischemic stress.
نویسندگان
چکیده
MEDICAL SCIENCES Correction for “mTORC1 maintains renal tubular homeostasis and is essential in response to ischemic stress,” by Florian Grahammer, Nora Haenisch, Frederic Steinhardt, Lukas Sander, Malte Roerden, Frederic Arnold, Tomke Cordts, Nicola Wanner, Wilfried Reichardt, Dontscho Kerjaschki, Markus A. Ruegg, Michael N. Hall, Pierre Moulin, Hauke Busch, Melanie Boerries, Gerd Walz, Ferruh Artunc, and Tobias B. Huber, which appeared in issue 27, July 8, 2014, of Proc Natl Acad Sci USA (111:E2817– E2826; first published June 23, 2014; 10.1073/pnas.1402352111). The authors note that the author name Lukas Sander should instead appear as Lukas Sandner. The corrected author line appears below. The online version has been corrected.
منابع مشابه
mTORC2 critically regulates renal potassium handling.
The mTOR pathway orchestrates cellular homeostasis. The rapamycin-sensitive mTOR complex (mTORC1) in the kidney has been widely studied; however, mTORC2 function in renal tubules is poorly characterized. Here, we generated mice lacking mTORC2 in the distal tubule (Rictorfl/fl Ksp-Cre mice), which were viable and had no obvious phenotype, except for a 2.5-fold increase in plasma aldosterone. Cha...
متن کاملاثر محافظت عصبی عصارهی اتانولی اسطوخودوس Lavandula officinalis)) بر میزان ادم مغزی در مدل سکتهی مغزی موش صحرایی
Background and Objective: Clinically significant changes in central nervous system (CNS) function are observed following brief periods of CNS blood flow interruption. Stroke patients exhibit cognitive, emotional, and electrophysiological changes during the recovery phase. Lavender belongs to the Labiatae family and is used for a variety of cosmetic and therapeutic purposes in herbal medicine. T...
متن کاملmTOR Regulates Endocytosis and Nutrient Transport in Proximal Tubular Cells.
Renal proximal tubular cells constantly recycle nutrients to ensure minimal loss of vital substrates into the urine. Although most of the transport mechanisms have been discovered at the molecular level, little is known about the factors regulating these processes. Here, we show that mTORC1 and mTORC2 specifically and synergistically regulate PTC endocytosis and transport processes. Using a con...
متن کاملI-33: Oxidative Stress Responses in EarlyPregnancy
Background: Survival of the conceptus is dependent on continuous progesterone signaling in the maternal decidua but how this is achieved under conditions of oxidative stress that characterize early pregnancy is unknown. Materials and Methods: Laboratory-based analysis of endometrial biopsies and primary endometrial cultures. Results: Using primary cultures, we show that modest levels of reactiv...
متن کاملuse of 99m Tc-DMSA scintigraphy in assessment of renal complications of COVID-19
ABSTRACT COVID-19 mainly affects respiratory and immune systems, but other organs like renal, cardiovascular, lung and nervous systems could also be involved in both acute and chronic settings (1, 2). There is a lot of studies that demonstrate an increasing number of long COVID-19 who continue to experience persistent symptoms weeks or even months after the initial disease. Reports suggest...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Proceedings of the National Academy of Sciences of the United States of America
دوره 112 49 شماره
صفحات -
تاریخ انتشار 2015